My friend has very bad brain fog from a physical condition. It’s so bad she often pauses when she speaks like a YouTube video trying to buffer on a bad internet connection and she told me she wants to be more like her former self. She’s on medication for the condition, but the brain fog is one symptom that persists. She wants some good insight on how effective amphetamines are for brain fog in the non-ADHD population. She could only find people who have both ADHD and brain fog which could skew things. She doesn’t have ADHD, just brain fog.

  • cynar@lemmy.world
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    28 days ago

    It likely won’t help, though it depends on the source of the brain fog. ADHD drugs are aimed particularly at the areas of the brain associated with executive functioning. Under stimulation here can cause brain fog, among other symptoms. Critically, the body’s homeostasis system wants to boost things, but can’t. It doesn’t fight the boost from the drugs, at least in the under stimulated areas.

    If the brain fog is sourced elsewhere in the brain then the amphetamines won’t help much. Even worse, a normal Brian will adapt to counter the drugs effect, causing physical addiction. You would need to constantly increase the dose to gain the same effect. That’s the reason ADHD drugs are controlled substances in most countries. People chase the dragon, and end up nuking their brain with too high a dose.

    Basically, don’t do it without medical oversight.

  • snek_boi@lemmy.ml
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    29 days ago

    Besides talking to a doctor, would she be against doing cognitive training?

  • recklessengagement@lemmy.world
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    29 days ago

    This sounds like a sleeping disorder, imo.

    And no, ADHD medications do not make you immune to brain fog. In some situations they can make it worse, especially when they wear off.

    Ask your friend if they’ve been checked for sleep apnea.

  • floo@retrolemmy.com
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    29 days ago

    That depends on how much amphetamines you take, and what type of amphetamines you take. The effects would varies slightly from person to person, but, generally speaking, amphetamines are extremely effective.

    • fubbernuckin@lemmy.dbzer0.com
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      28 days ago

      The effects vary a lot from person to person. For me, amphetamines cause brain fog. I remember years ago when I was first prescribed them, they worked great to treat my ADHD. I never felt any addictive tendencies and could stop using them for extended periods without any cravings or even withdrawal symptoms. Around the end of high school they started to give me horrible brain fog though, it would take me a few seconds to even recognize my name, I had a hard time remembering where I was or how I got there, it was pretty bad. I stopped using them pretty shortly after I figured out the cause of my symptoms. Definitely best to talk to a doctor about it, don’t assume it’s going to work for you.

  • kungen@feddit.nu
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    29 days ago

    She should discuss that with a doctor instead of self-medicating with addictive substances.

    • Durian@lemmy.cafeOP
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      29 days ago

      She’s looking to mention her brain fog and how she needs it to improve on her next appointment. It’s often prescribed for brain fog in some places. Her brain fog is bad enough that directions like left/right take up to 5 seconds to compute and she keeps telling me how embarrassing it is

  • pelgraine@lemmy.world
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    29 days ago

    As someone who takes dexamphetamine daily for ADHD, it doesn’t fix my brain fog caused by other factors. There’s a number of things that can be causing the brain fog for your friend, and I wouldn’t recommend starting with amphetamines.

    For myself I’ve been looking into the anti-inflammatory potential of drugs like semaglutide or tirzepatide as a possibility. For the most part, keeping my allergies in check and my thyroid levels as close to ideal for me as I can get helps way more with fatigue and brain fog than the ADHD drugs do.

  • LainTrain@lemmy.dbzer0.com
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    28 days ago

    I could see it being effective, yeah. Obviously in this situation she just needs to try it (carefully obvs) and report the effects. If it’s not/won’t be medically prescribed for her condition then she would be in somewhat untested waters, so it’s a trial and error thign obviously keep it safe and acetone wash it.

    When I was self-medding with amph, I bought a scale and would pack it in capsules weighed out to 40mg each and pop two - four a day. Don’t snort that shit.

    Definitely don’t do Cocaine that shit doesn’t help much of anything and even if it seems to, lasts all of 10 minutes unless you OD.

    I would also suggest wellbutrin. It’s sometimes used as a generic stim, but unlike amph and etc. it’s also a smoking cessation aid - because it works on the nicotinic receptor, similar effect to nicotine but without the addiction (and in fact,.you won’t want to ever consume nicotine on it).